Yan Zhou
Postdoctoral Research Fellow
- City/country of origin
- Nanjing/China
- Hobbies
- Painting, tennis, traveling, amateur modeling
- Places You Like
- Beach and forest
- Where for a big vacation
- Europe
- What are your strong points?
- Patience, optimism
- What are people in the lab doing?
- Pipetting
- What was surprising about the suga lab
- The lab has many labs and a wide range of equipment
- Original motivation towards science?
- Create change
- A few words for future lab mates
- Nice to meet you ^_^
- Science is…….
- similar to cooking
Education & professional career
- 2025
- Postdoctoral Research Fellow, The University of Queensland
- 2021-2024
- Doctor of Philosophy, The University of Queensland
- 2020-2021
- Bachelor of Science (Honours), The University of Queensland
Publications
- "Asparaginyl Ligases with Engineered Substrate Specificity for Controlled, Sequential Transpeptidation Reactions."
- Y. Zhou; S.J. de Veer; T.J. Tyler; Y. Chen; T. Durek; D.J. Craik; F.B. Rehm
- Journal of the American Chemical Society, (2025)
- "AEP-mediated backbone cyclization of cyclotides-A chemoenzymatic method for cyclotide production."
- Y. Zhou; S.J. de Veer; T. Durek; D.J. Craik
- Methods in Enzymology, 723, 71-90 (2025)
- "A chemo-enzymatic approach to produce a cyclic analogues of peptide drug leads."
- Y. Zhou; P. Harvey; T. Durek; D. Craik
- Journal of Peptide Science, 30, (2024)
- "Sortase‐Catalyzed Protein Domain Inversion."
- Y. Zhou; T. Durek; D.J. Craik; F.B. Rehm
- Angewandte Chemie, 136, e202316777 (2024)
- "Repurposing a plant peptide cyclase for targeted lysine acylation."
- F.B. Rehm; T.J. Tyler; Y. Zhou; Y.-H. Huang; C.K. Wang; N. Lawrence; D.J. Craik; T. Durek
- Nature Chemistry, 16, 1481-1489 (2024)
- "Tertiary amide bond formation by an engineered asparaginyl ligase."
- S.J. de Veer; Y. Zhou; T. Durek; D.J. Craik; F.B. Rehm
- Chemical Science, 15, 5248-5255 (2024)
- "A chemoenzymatic approach to produce a cyclic analogue of the analgesic drug MVIIA (Ziconotide)."
- Y. Zhou; P.J. Harvey; J. Koehbach; L.Y. Chan; A. Jones; Å. Andersson; I. Vetter; T. Durek; D.J. Craik
- Angewandte Chemie International Edition, 62, e202302812 (2023)
- "Cyclotides—cyclic and disulfide-knotted polypeptides."
- D.J. Craik; Y. Zhang; Y. Zhou; Q. Kaas; M.-W. Kan
- Topological Polymer Chemistry: Concepts and Practices (Springer), pp. 135-147
- "Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases."
- K. Yap; J. Du; F.B. Rehm; S.R. Tang; Y. Zhou; J. Xie; C.K. Wang; S.J. de Veer; L.H. Lua; T. Durek
- Nature Protocols, 16, 1740-1760 (2021)
Contact info
-
- E-mail… yanzhou"at"g.ecc.u-tokyo.ac.jp (change "at" to @)